Microbrachytherapy in pancreatic cancer

With microbrachytherapy we implant microscopically small radioactive microspheres into pancreatic cancer. With direct delivery of the microspheres into the tumor, as well as guidance by CT imaging during the procedure, we aim to achieve the optimal and safest intervention. The radioactive isotope incorporated into the microspheres, holmium-166, irradiates the tumor from the inside out for approximately 10 days. Thereafter, all radiation is gone, and the microspheres remain implanted..


This project started in 2020, and currently one fundamental and two clinical trials have successfully been completed. The main outcomes of these studies indicate that intratumoral injection of holmium-166 microspheres in irresectable pancreatic cancer is feasible and very safe. Future studies are being planned to determine effectiveness.


Note: no clinical trials to this intervention are currently being performed and it is not possible to receive this intervention. For questions regarding clinical trials or experimental treatment, ask your general practitioner or treating physician.