Publications
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Spatial distribution of fractionally administered holmium microspheres in non-tumorous human liver tissue: how livers survive transarterial radioembolisation
A. van den Brekel, T.J. Snoeijnk, V.E. de Meijer, M. Boswinkel, K.P. de Jong, J. Roosen, A.G. Arranja, J.J. Fütterer, S.J.S. Ruiter, J.F.W. Nijsen Background: Relatively high mean absorbed doses to the non-tumorous liver tissue (NTLT) are generally...
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Irreversible electroporation: maximizing treatment efficacy through optimization strategies and robotic assistance
Irreversible electroporation (IRE) is a non-thermal ablation technique that uses an electric field to destroy tumor cells. The distribution of the electric field within the targeted tissue is critical for successful treatment. Achieving complete...
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Jessie Swarts
aspects of ablative and transarterial therapies in patients with hepatocellular carcinoma. She is supervised by Jurgen Fütterer, Frank Nijsen, and Kristian Overduin from the Department of Medical Imaging, and Eric Tjwa from the Department of...
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Evaluation of a novel forward-looking optical coherence tomography probe for endoscopic applications: an ex vivo feasibility study
F.J.C. Jacobs, V. Groenhuis, I.M. de Jong, I.D. Nagtegaal, M.M. Rovers, G.J. Bulte, J.J. Fütterer Background: As a result of recent advances in the development of small microelectromechanical system mirrors, a novel forward-looking optical coherence...
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Evaluating Biparametric Versus Multiparametric Magnetic Resonance Imaging for Diagnosing Clinically Significant Prostate Cancer: An International, Paired, Noninferiority, Confirmatory Observer Study
O. Rouvière, R. van den Bergh, V. Panebianco, V. Kasivisvanathan, N.A. Obuchowski, D. Yakar, M. Elschot, J. Veltman, J.J. Fütterer, H. Huisman, M. de Rooij; PI-CAI Consortium Background and objective: Biparametric magnetic resonance imaging (bpMRI),...
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Intraprocedural MRI-based dosimetry during transarterial radioembolization of liver tumours with holmium-166 microspheres (EMERITUS-1): a phase I trial towards adaptive, image-controlled treatment delivery
J. Roosen, L.E.L. Westlund Gotby, M.J. Arntz, J.J. Fütterer, M.J.R. Janssen, M.W. Konijnenberg, M.W.M. van Wijk, C.G. Overduin, J.F.W. Nijsen Purpose Transarterial radioembolization (TARE) is a treatment for liver tumours based on injection of...
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Intraoperative imaging and image-guidance in the hybrid operating room: benign bone tumors and bone metastases
The hybrid operating room (OR) is a specialized OR that combines a traditional OR with the latest intraoperative imaging technology. The hybrid OR, with all its facilities, is more expensive than an angiography suite or a standardly equipped OR. It is...
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Explorative Identification of Anatomical Parameters Associated with Successful Pessary Fitting in Pelvic Organ Prolapse Using Dynamic Magnetic Resonance Imaging
C.P.R. Triepels, L.L. Boogaard, J.J. Fütterer, S.M.J. van Kuijk, W.A. Spaans, R.F.P.M. Kruitwagen, M. Weemhoff, K.J.B. Notten Background: Pelvic organ prolapse (POP) affects many women and is often managed with pessary treatment, yet predicting the...
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Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study
O. Rouvière, R. van den Bergh, V. Panebianco, V. Kasivisvanathan, N.A. Obuchowski, D. Yakar, M. Elschot, J. Veltman, J.J. Fütterer, M. de Rooij, H. Huisman; PI-CAI Consortium Background: Artificial intelligence (AI) systems can potentially aid the...
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IRE made easy: introducing the robotic grid system for multiple parallel needle insertion in irreversible electroporation treatment
G. Wardhana, J.J. Fütterer, M. Abayazid Purpose Accurate needle placement is crucial for successful tumor treatment using the irreversible electroporation (IRE) method. Multiple needles are inserted around the tumor, ideally in parallel, to achieve...
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Ultrasound imaging in breast cancer and neuromuscular disorders: Methods for quantitative and three-dimensional imaging
Ultrasound (US) is a very commonly used imaging technique in clinical care. Many applications include the use of US imaging because it is an effective, safe and efficient tool. Even though US has been available to clinics for decades, continuous...
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Feasibility of stereotactic optical navigation for needle positioning in percutaneous nephrolithotomy
I.M. Spenkelink, X. Zhu, J.J. Fütterer, J.F. Langenhuijsen Background: This study assessed the feasibility of acquiring single-attempt access to the pelvicalyceal system during percutaneous nephrolithotomy (PCNL) using stereotactic optical navigation...
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Mechanical high-intensity focused ultrasound creates unique tumor debris enhancing dendritic cell-induced T cell activation
van den Bijgaart, V.E. Mekers, F. Schuurmans, T.K. Raaijmakers, M. Wassink, A. Veltien, E. Dumont, A. Heerschap, J.J. Fütterer, G.J. Adema. Introduction: In situ tumor ablation releases a unique repertoire of antigens from a heterogeneous population of...
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Considerations for artificial intelligence clinical impact in oncologic imaging: an AI4HI position paper
L. Marti-Bonmati, D. Koh, K. Riklund, M. Bobowicz, Y. Roussakis, J. C. Vilanova, J.J. Fütterer, J. Rimola, P. Mallol, G. Ribas, A. Miguel, M. Tsiknakis, K. Lekadir, G. Tsakou To achieve clinical impact in daily oncological practice, emerging AI-based...
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Investigating the effect of electrode orientation on irreversible electroporation with experiment and simulation
G. Wardhana, N.M. Raman, M. Abayazid, J.J. Fütterer Purpose In recent years, irreversible electroporation (IRE) has been developed to specifically destroy undesirable tissues as an alternative to surgical resection. In this treatment, placing multiple...
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Current State of MRI-Guided Endovascular Arterial Interventions: A Systematic Review of Preclinical and Clinical Studies
H. Nijsink, C.G. OVerduin, L.H. Willems, M.C. Warlé, J.J. Fütterer Background MRI guidance of arterial endovascular interventions could be beneficial as it does not require radiation exposure, allows intrinsic blood-tissue contrast, and enables...
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The lymphatic system throughout history: From hieroglyphic translations to state of the art radiological techniques
C.J. van Schaik, L.L. Boer, J.M.T. Draaisma, C.J.M. van der Vleuten, J.J. Janssen, J.J. Fütterer, L.J. Schultze Kool, W.M. Klein A comprehensive lymphatic system is indispensable for a well-functioning body; it is integral to the immune system and is...
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AI-assisted biparametric MRI surveillance of prostate cancer: feasibility study
C. Roest, T.C. Kwee, A. Saha, J.J. Fütterer, D. Yaker, H. Huisman Objectives To evaluate the feasibility of automatic longitudinal analysis of consecutive biparametric MRI (bpMRI) scans to detect clinically significant (cs) prostate cancer (PCa)....
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Feasibility of a Prototype Image Reconstruction Algorithm for Motion Correction in Interventional Cone-Beam CT Scans
I.M. Spenkelink, J. Heidkamp, R.L.J. Verhoeven, S.F.M. Jenniskens, A. Fantin, P. Fischer, M.M. Rovers, J.J. Fütterer Rationale and objectives: Assess the feasibility of a prototype image reconstruction algorithm in correcting motion artifacts in...
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Liver-tumor mimics as a potential translational framework for planning and testing irreversible electroporation with multiple electrodes
A.L. Vera-Tizatl, R. van der Hee, J. Cornelissen, C.E. Vera-Tizatl, M. Abayazid, J.J. Fütterer Irreversible electroporation (IRE) has emerged as an appealing non-ionizing, non-thermal ablation therapy, independent of antineoplastic drugs. Limited but...