Publications
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Artificial Intelligence × Prostate Cancer Detection on MRI
This thesis examines the development and validation of AI systems for prostate cancer detection on MRI, with the aim of generating robust evidence to guide their integration into clinical workflows. To this end, it examined three central questions: (1)...
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Artificial Intelligence and Biparametric MRI in Prostate Cancer Detection: From Benchmarking to Workflow Strategies
Prostate cancer is one of the most common cancers in men. MRI helps detect aggressive cancer accurately and on time, but interpretation is complex and requires a high level of expertise. At the same time, pressure on healthcare systems is increasing...
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Omar Hussein
tip localization of needles in MRI using Superparamagnetic Iron Oxide Nanoparticles (SPIONs). He is supervised by Jurgen Fütterer.
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Nynke Dijkhuis
liver metastases and prostate cancer through margin quantification. She is supervised by Kristian Overduin and Jurgen Fütterer.
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Unravelling the distribution of holmium microspheres following transarterial radioembolisation
Transarterial radioembolisation is a treatment for liver cancer that delivers radioactive microspheres into the liver via a blood vessel. These microspheres spread unevenly: some areas in the liver receive high radiation dose, others very little. In...
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Matthijs Topper
to support ablation procedures for hepatocellular carcinoma, using CT imaging data. His work is supervised by Jurgen Fütterer and Kristian Overduin.
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Quantifying hepatic arterial blood flow with 4D flow MRI: an in vivo feasibility and repeatability study
van den Brekel, Marnix C Maas, Ilse M Spenkelink, Willem C M van Tilburg, Joey Roosen, Daniel Giese, Ning Jin, Jurgen J Fütterer, J Frank W Nijsen Objective: To investigate the feasibility and repeatability of four-dimensional (4D) flow MRI for...
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Real-Time Deep-Learning Image Reconstruction and Instrument Tracking in MR-Guided Biopsies
Constant R Noordman, Lauren P W Te Molder, Marnix C Maas, Christiaan G Overduin, Jurgen J Fütterer, Henkjan J Huisman Background: Transrectal in-bore MR-guided biopsy (MRGB) is accurate but time-consuming, limiting clinical throughput. Faster imaging...
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Dose heterogeneity in transarterial radioembolization after fractional administration of holmium microspheres: a study in perfused human tumor-bearing liver explants under MRI
Arja Gerritsen, Milou Boswinkel, Joey Roosen, Alexandra G Arranja, Marius C van den Heuvel, Cyril Moers, Jurgen J Fütterer, Koert P de Jong, Vincent E de Meijer, Simeon J S Ruiter, J Frank W Nijsen Purpose: To investigate dose heterogeneity in liver...
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Germen Wennemars
on navigation of passively marked devices in MR-guided interventions. He is supervised by Kristian Overduin and Jurgen Fütterer.
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Jelle van der Pas
solution for use in image-guided interventions, using CT-fluoroscopy images as input. His project is supervised by Jurgen Fütterer.
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Development of an Intratumoral Holmium Microsphere Injection Method in Ex Vivo Human Pancreatic Ductal Adenocarcinoma: A Preclinical Feasibility Study
Nienke Johanna Maria Klaassen, Martijn Willem Jan Stommel, Cornelis Johannes Henricus Martinus van Laarhoven, Jurgen J Fütterer, Johannes Frank Wilhelmus Nijsen Background/objectives: Patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) have...
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AI-Assisted vs Unassisted Identification of Prostate Cancer in Magnetic Resonance Images
Roderick van den Bergh, Veeru Kasivisvanathan, Nancy Obuchowski, Derya Yakar, Mattijs Elschot, Jeroen Veltman, Jurgen Fütterer, Henkjan Huisman, Maarten de Rooij; PI-CAI Consortium Importance: Artificial intelligence (AI) assistance in magnetic...
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CT-guided Thermal Ablation of Liver Tumors Using Intraprocedural CT-CT Fusion for Applicator Position and Ablation Completeness Assessment: a Single-Center Comparative Analysis
Koen H M Verdonschot, Sjoerd F M Jenniskens, Peter B van den Boezem, Eric T T L Tjwa, Johannes H W de Wilt, Jurgen J Fütterer, Martijn W J Stommel, Christiaan G Overduin Purpose: To compare outcomes of CT-guided thermal ablation of liver tumors with...
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Intratumoral Holmium-166 Microsphere Injection in Patients with Unresectable Pancreatic Ductal Adenocarcinoma: A Single-Center, Single-Arm, Open-Label Feasibility and Safety Study
Jenniskens, Martijn W J Stommel, Marcel J R Janssen, John J Hermans, Harm Westdorp, Cornelis J H M van Laarhoven, Jurgen J Fütterer, J Frank W Nijsen Introduction: Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and lacks local treatment...
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3D analysis improves outcomes of image-guided liver tumor treatment
H. M. Verdonschot, Sjoerd F. M. Jenniskens, Peter B. van den Boezem, Eric T. T. L. Tjwa, Johannes H. W. de Wilt, Jurgen J. Fütterer, Martijn W. J. Stommel & Christiaan G. Overduin DOI: 10.1007/s00270-025-04111-w
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Prof. Jurgen Fütterer presented his inaugural lecture
On 3 July 2025, Prof. Jurgen J. Fütterer provided his inaugural lecture as Chair of Image-Guided Oncological Interventions. During his inaugural lecture, titled "Precisie in Beeld: Minimaal Invasieve Oncologische Interventies", he emphasized the...
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The role of technological innovations in CT-guided minimally invasive procedures
Minimally invasive treatments offer many advantages for patients compared to traditional open surgeries. They are safer, cause less damage to the body, and allow patients to recover more quickly. This thesis explores how new technologies can make these...
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Spatial distribution of fractionally administered holmium microspheres in non-tumorous human liver tissue: how livers survive transarterial radioembolisation
A. van den Brekel, T.J. Snoeijnk, V.E. de Meijer, M. Boswinkel, K.P. de Jong, J. Roosen, A.G. Arranja, J.J. Fütterer, S.J.S. Ruiter, J.F.W. Nijsen Background: Relatively high mean absorbed doses to the non-tumorous liver tissue (NTLT) are generally...
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Irreversible electroporation: maximizing treatment efficacy through optimization strategies and robotic assistance
Irreversible electroporation (IRE) is a non-thermal ablation technique that uses an electric field to destroy tumor cells. The distribution of the electric field within the targeted tissue is critical for successful treatment. Achieving complete...
